Happ pulled Marlins pitcher Jose Urena’s first-pitch fastball over the right-field fence at Marlins Park, giving Chicago a 1-0 lead.
Addison Russell and Jason Heyward added further runs as Urenas needed three dozen more pitches to get out of the first inning.
Brian Anderson drove in a run for the Marlins in the first, only for Anthony Rizzo to restore the Cubs’ three-run advantage with a homer in the second.
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